Global Scientific Review

The Importance Of Endothelial Dysfunction Gene Polymorphisms In The Development Of Chronic Venous Insufficiency Of The Lower Extremities

Kakharov A. N, Vasilevskiy E. A, Kurbonboev B. N, Khuzhamberdiev I. R. — Sat, 02 Nov 2024 00:00:00 +0000

In 98 patients, an analysis of the genetic risk factor for the development of chronic venous insufficiency was carried out by studying the frequency of distribution of alleles and genotypes of the C936T polymorphism in the VEGFA gene. In both groups, the actual distribution of C807T polymorphism genotypes corresponded to those expected under the Hardy-Weinberg equilibrium (p

<0.05). A significant relationship was established between the risk of developing chronic venous insufficiency and the distribution of predisposing/protective variants of the C807T polymorphism genotypes in the VEGFA gene. These data allow us to suggest testing this locus to predict the risk of occurrence and progression of chronic venous insufficiency.>

Principles Of Treatment Of Patients With Chronic Kidney Disease And Arterial Hypertension

N.M Abdurakhmanova, O.M. Norbo‘toyev — Fri, 08 Nov 2024 00:00:00 +0000

Chronic kidney disease (CKD) is a progressive kidney injury, more common in the elderly, women, patients with diabetes mellitus (DM) and/or arterial hypertension (AH). Currently, CKD is recognized as one of the leading causes of death worldwide. Another medical and social problem is hypertension, which is the most important cardiovascular risk factor worldwide and one of the main causes of CKD. The high prevalence and comorbidity of CKD and hypertension, as well as an unfavorable prognosis, determine the need for effective prevention and treatment of these conditions. The use of nephroprotective approaches in the treatment of CKD can significantly improve the prognosis both in patients with risk factors for the development of renal dysfunction and in patients with existing kidney disease. According to modern recommendations for the treatment of hypertension, patients with high-risk hypertension, including from the standpoint of nephroprotection, are shown combination therapy with drugs from two groups, preferably in one tablet. The article presents data confirming the efficacy of a fixed combination of an angiotensin-converting enzyme inhibitor and a dihydropyridine calcium channel blocker.

The Effectiveness of a Training Program Based on The Use of Resistance to Sand Frictions on The Improvement of Some Physical and Skill Variables Among Roman Wrestling Players

Assistant Lecturer, Samer Mahdi Saleh — Fri, 08 Nov 2024 00:00:00 +0000

The objective of the study was to determine the efficacy of a training program utilizing sand friction resistance in enhancing several physical and skill variables in Romanian wrestling athletes. The study introduced a theoretical structure that encompassed sports training, sand training, physical performance, and skill performance. The study utilized the experimental methodology. The research equipment comprised a racemeter, a stopwatch, a measuring tape, measuring ropes, rubber ropes, weighted medicine balls, iron bars, hurdles, wrestling bars, jump ropes, weight jackets, iron hurdles, and a test involving running, pulling up, bridging, and response speed. A sample of (20) Romanian wrestling players under the age of (17) in the Minya Governorate clubs were subjected to the action of broad jump. The participants were placed into two groups: an experimental sample consisting of 10 players, and a control sample consisting of 10 players from the Military Institution Club in Minya. The research findings verified that implementing a sand resistance training program effectively enhances the physical and skill attributes of Romanian wrestling players. The research suggests prioritizing structured training programs for wrestling players, since these programs have been found to enhance both the physical and skill aspects of the sport. Implementing such programs is crucial for elevating the performance level of players.

Prospects for the development of electronic money as one of the development directions of the payment system

Shokhsanam Shirinova — Fri, 08 Nov 2024 00:00:00 +0000

This article discusses issues that are associated with such a concept as "electronic money". Information on electronic money based on smart cards and networks is presented, as well as characteristics of payment systems in the Uzbek segment of the Internet are described. The basic concepts and perspective directions of development of the electronic payment system are also considered. This article examines the tools for monetary regulation and recommendations for improving them to increase the coefficient of monetization of the economy

Comparative Description Of Anthropometric Indicators Of Nutritional Strategy In Practitioners With An Ectomorph Body Structure

U.Sh.Valikhanov — Fri, 08 Nov 2024 00:00:00 +0000

This study demonstrates the impact of proper nutrition on the engaging form of athletic gymnastics, a healthier type of gymnastics. Observations were conducted on second-year students of the Faculty of Physical Culture of Andijan State University. Through the study, the study described how the effectiveness of athletic exercise in determining the anthropometric performance of students depends on the proper organization of nutrition. The importance of supplemental nutrition for ectomorphic individuals by body type has been demonstrated

Architecture Of The Palace Gardens Of The Bukhara Emirate: Sitorai Mohi Khosa

Rustam Batirjonovich Abdurakhimov, Rustam Batirjonovich Abdurakhimov — Fri, 08 Nov 2024 00:00:00 +0000

This article discusses the Sitorai Mohi Khosa palace garden, built in the late 19th and early 20th centuries in Bukhara. The article explores the architectural and compositional solutions of the palace, its traditional artistic decorations, and the integration of both modern and national architectural styles and elements. The creative works of the architects and craftsmen involved in its construction are also examined

Approach To The Question Of Truth In The History Of Philosophy

Suhrob Panjiyev — Sat, 16 Nov 2024 00:00:00 +0000

The article compares comparatively the views of philosophers of modern Western philosophers F. Bacon, R. Descartes, G.V. Leibniz, J. Locke, I. Kant and Hegel on the criterion of truth.

The effect of a proposed educational program using specific exercises to develop motor response, motor satisfaction, and short-term defensive movement skills in handball

Thu, 28 Nov 2024 00:00:00 +0000

This research aims to evaluate the effectiveness of a specific educational program in improving the motor performance of handball players by measuring its effect on motor response speed, increasing motor satisfaction, and improving limited defensive movement skills. The experimental method was used, and the players of the AlTaawon Sports Club junior category represented the research sample. The researchers used the motor response speed test to measure the motor response time with a visual stimulus, the motor satisfaction scale to identify the degree of individual satisfaction with his movements and motor and physical characteristics, and the short-term defensive movements test to measure the player's speed in short-term defensive movements. After conducting the pre-tests and implementing the educational program, then conducting the post-tests, the data were recorded and organized in specific tables to obtain the test results using the following statistical methods: the arithmetic mean, the standard deviation, and the calculated (t) value. The calculated t-values showed statistically significant differences (p

<0.05) between the pre- and post-measurements in all variables, indicating a positive effect of the training program on the